Through the action of an oxidoreductase enzyme, the inactive form is rapidly converted to ubiquinol, the lipid-soluble form that may support antioxidant activity throughout the body. Conversion of inactive form to ubiquinol declines with age, particularly after age 40. Supplementation may help maintain normal levels of ubiquinol in the body as well as address drug-induced nutrient depletion of CoQ10.
Until recently, the ubiquinol form had not been effective as a supplement because it was chemically unstable and easily oxidized. Ubiquinol-100 contains a patented, absorbable form of ubiquinol that may help maintain its structure and stability in the gastrointestinal environment.
Oxidative stress is detrimental to the integrity and function of cell membranes and tissues, and ultimately to DNA itself. Antioxidant status must be maintained throughout the body in order to protect vulnerable cells. Research indicates that ubiquinol supports antioxidant activity, including the regeneration of vitamins C and E, which may help to maintain normal levels of free radical activity in the body. Researchers also suggest a possible role for CoQ10 in redox control of cell signaling and gene expression.
Antioxidant protection is vital to maintaining the integrity of cholesterol and its role as a precursor to vitamin D, hormones, cell membranes, and brain tissue. Reactive oxygen species, including superoxide released by immune cells, cause the oxidation of cholesterol and can turn a vital biochemical precursor into a toxin.
Toxicity: CoQ10 is safe as a dietary supplement. Toxicity is unlikely up to a daily intake of 1200 mg/d, although typical dosages have been 100 to 200 mg/d. In preclinical studies, ubiquinol's No-Observed-Adverse-Effect Level is 300-600 mg/kg.
Enhancing Healthcare Team Outcomes: CoQ10 is a safe, popular dietary supplement that is continuously being studied as an adjunctive treatment for several medical conditions, including congestive heart failure, type-2 diabetes mellitus with hyperlipidemia, fibromyalgia, mitochondrial disorders, Peyronie disease, myalgia, depression, migraines, and polycystic ovary syndrome.
For more comprehensive information on Ubiquinol, please follow the link to this article published in the National Library of Medicine: https://www.ncbi.nlm.nih.gov/books/NBK531491/
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
