Diosmin is a well-researched citrus flavonoid that has been utilized for decades to support healthy capillary and vein function as well as healthy microcirculation throughout the body. Diosmin fundamentally helps maintain the structure and function of the circulatory system, especially vein strength and competence. The most promising research results come from a micronized purified flavonoid fraction comprising 450 mg of diosmin and 50 mg of hesperidin (hesperidin is a precursor to diosmin). This is the same ratio and dose found in each DioVasc capsule. The process of micronization (reducing particle size to less than two micrometers in diameter) improves diosmin absorption.
Micronized purified flavonoid fraction (MPFF) appears to support vein health by prolonging the normal effect that the catecholamine norepinephrine has on the vessel wall; and this, therefore, promotes venous tone. Research also suggests that MPFF affects the synthesis of prostaglandins and free radicals, as well as leukocyte activation, trapping, and migration. Ultimately, MPFF supports antioxidant systems and eicosanoid balance.
Pharmacological and clinical studies suggest that MPFF—on its own and in conjunction with standard therapy—promotes normal lymph drainage, healthy capillary permeability, and favorable microcirculation. Multicenter, prospective, randomized, controlled studies document the effect of MPFF on maintaining healthy venous sufficiency. Two randomized, double-blind,
placebo-controlled studies conducted over a two-month period demonstrated the venotropic nature of DioVasc’s main component. Significant support of organic and functional parameters occurred along with significant support of venous hemodynamics. Some studies indicate that favorable results can be achieved within two hours of administration.
» Supports Veins, Capillaries, and Circulation
» Helps Promote Normal Lymphatic Drainage
» Supports Antioxidant Activity
» Supports Blood Glucose Metabolism
» Supports Healthy Eicosanoid Metabolism