CoQnol™ 200 features a unique combination of ubiquinol and trans-geranylgeraniol (GG). The GG complements the actions of ubiquinol by enhancing absorption and supporting endogenous CoQ10 synthesis naturally in the body. This formula provides 200 mg of ubiquinol as DuoQuinol™ and 125 mg of trans-geranylgeraniol as GG-Gold® per serving, a patented form of GG extracted from annatto seeds, along with quillaja extract for enhanced absorption and bioavailability.
The body uses two forms of COQ10. Ubiquinone is the better known form, also known as the oxidized form, used primarily for energy production in the electron transport energy cycle inside the cell.
CoQnol contains ubiquinol, the reduced, antioxidant form of CoQ10. Ubiquinol plays a primary role of decreasing oxidative damage caused by lipid peroxidation within mitochondria. According to research, plasma ubiquinol is decreased in patients with hyperlipidemia.
There is evidence that suggests that the ability to convert ubiquinone to ubiquinol may diminish with age, resulting in diminished protection against oxidative stress and reduced energy levels. CoQnol (ubiquinol) may provide a strong initial stage defense against cellular oxidative damage and requires supplementing to maintain optimum health. Consider taking CoQnol along with QAvail, highly absorbable ubiquinone.
Researchers at East Texas Medical Center found that patients with advanced congestive heart failure taking high doses of ubiquinone CoQ10 were not able to achieve adequate improvements in blood serum CoQ10 levels. When switched to ubiquinol, blood COQ10 levels improved dramatically with a consequential improvement in clinical symptoms and left ventricular function. It is also being studied for its effects on TNF alpha, and therefore, inflammation.