Since 1992, lumbrokinase derived from earthworms has been extensively studied and used in China. Research has shown lumbrokinase to support healthy coagulation of blood within normal levels and enhance fibrinolytic activit, i.e. similar to nattokinase.
The lumbrokinase group of proteolytic enzymes, extracted from Lumbricus Rubellus, includes plasminogen activator and plasmin. The plasminogen activator (e-PA) in lumbrokinase is similar to tissue in plasminogen activator (t-PA) from other sources, which makes it possible to show the thrombolytic activity only in the presence of fibrin. Therefore, lumbrokinase has the advantage of not causing excessive bleeding.