This standardized extract from the Chinese club moss has potent beneficial effects on the metabolism of acetylcholine, a neurotransmitter well known for its importance to memory, cognition and attention, with additional implications for brain aging and longevity. In fact, Huperzine A powerfully modulates the activity of acetylcholinesterase, the enzyme that destroys acetylcholine. Huperzine A can cross the blood-brain barrier, indicating its excellent oral bioavailability, and it has a long duration of bioactivity. This makes Huperzine A both powerful and promising as a neuroprotectant.