4sight was formulated with a specific blend of botanicals, nutrients, antioxidants and minerals shown in research to support healthy eye function. The formula provides key antioxidant support and nutrients to care for and maintain the long-term health of the eyes.

In the United States, eye health is a major concern for those over 60 years of age. The eye is the organ most susceptible to oxidative damage caused by light, toxins (smoke), atmospheric oxygen and abrasion. As ultraviolet and blue light pass through the retina to the photoreceptors (rods and cones) and the pigmented epithelial (PE) cells, reactive oxygen species (free radicals) are generated. If there are insufficient antioxidants available to neutralize free radicals, the eye undergoes excessive oxidative damage.

Alpha Lipoic Acid

Alpha lipoic acid (ALA) is a potent, versatile antioxidant that is both water- and fat-soluble. ALA has been shown to inhibit aldose reductase, which prevents sorbitol-induced leakage of important antioxidants from eye tissues and recharges ALA, vitamin C, vitamin E and glutathione.

Ginkgo biloba

Ginkgo biloba extract is a well-studied botanical that increases cerebral blood flow and protects neurons from a variety of conditions and oxidant-induced damage. It scavenges NOS (nitric oxide species) and ROS (reactive oxygen species), supports mitochondrial function, inhibits NMDA receptor activation, antagonizes PAF (platelet activating factor), and stimulates the release of NOS to support cerebral blood flow. It has been shown to provide key antioxidant support for eyes.

Carotenoids: Lutein, Zeaxanthin, Lycopene

Lutein and zeaxanthin are carotenoid pigments whose role in eye health is well-established from epidemiological, clinical and interventional studies. Epidemiologic research shows a connection between high levels of lutein and zeaxanthin in eye tissues and enhanced eye function and visual acuity. Lutein and zeaxanthin supplementation has been shown to protect the lens protein, lipid and DNA from oxidative damage and improve intracellular redox status under oxidative stress. Increased dietary intake of carotenoids, especially lutein and zeaxanthin, protect the eye from oxidative stress.

Zinc

A vital coenzyme for eye tissue, zinc is a necessary component in antioxidant enzymes, including superoxide dismutase, glutathione peroxidase and catalase. The enzymes responsible for digesting rod outer segments and preventing the build-up of lipofuscin, a lipid-containing residue caused by normal “wear and tear” that can impair vision, are significantly less active in older individuals. These important enzymes can be stimulated by adding zinc.

Bilberry

Bilberry extract contains a high amount of antioxidants known as anthocyanadins, similar to those found in grape seeds. Bilberry has a long history of use in eye health. Its activities include inhibition of aldose reductase, and improving capillary permeability. Bilberry has been shown to protect against an oxidative stress-induced immune response in the mouse uvea and to support night vision. The extract has also been found to support renewal and homeostasis of corneal cells.

Quercetin

A flavonoid found in a variety of herbs, vegetables and fruits, quercetin provides key antioxidant support for eyes.

Taurine

Taurine concentration is high in the retina and is required for retinal tissue growth. It has been shown to protect rod outer segments from oxidative damage and to protect lens tissue from radiation. Researchers have suggested possible functions for taurine in the retina include protection of the photoreceptor, regulation of Ca2+ transport, and regulation of signal transduction.

Ingredients:

Zinc, Taurine, N-Acetyl-L-Cysteine, Alpha Lipoic Acid, Bilberry Fruit Extract, Quercetin Dihydrate, Ginkgo biloba, Lutein, Lycopene, Zeaxanthin

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.